Impaired wound healing results from the dysfunction of the Akt/mTOR pathway in diabetic rats. Issue 3 (September 2015)

• Record Type: Journal Article
• Authors: Huang, Hong; Cui, Wenhui; Qiu, Wei; Zhu, Ming; Zhao, Rongshen; Zeng, Dengfen; Dong, Chenhui; Wang, Xiaohui; Guo, Wei; Xing, Wei; Li, Xiangyun; Li, Lei; Tan, Yan; Wu, Xiaofeng; Chen, Lizhao; Fu, Xiaobing; Luo, Donglin; Xu, Xiang
• Is Part Of: Journal of dermatological science. Volume 79:Issue 3(2015:Sep.)
• Page Start: 241
• Page End: 251
• Publication Date: 2015-09
• Subjects: Dermatology -- Periodicals; Skin Diseases -- Periodicals; Dermatologie -- Périodiques; 616.5005
• DOI: 10.1016/j.jdermsci.2015.06.002
• Languages: English
• ISSNs: 0923-1811

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0035"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Wound healing is impaired in diabetes mellitus. The underlying mechanisms involved in this process are virtually unknown.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">The Akt/mTOR signaling pathway plays a pivotal role in the pathogenesis of diabetes.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">The Akt/mTOR signaling pathway participates in wound repair.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">The dysfunction of this pathway in diabetes may result in the pathophysiological characteristics of diabetic skin and impaired wound healing.</p> </list-item> </list> </p> </sec> </abstract>