Endogenous Endophthalmitis. Issue 5 (September 2015)

• Record Type: Journal Article
• Authors: Ratra, Dhanashree; Saurabh, Kumar; Das, Debmalya; Nachiappan, Kasinathan; Nagpal, Amit; Rishi, Ekta; Bhende, Pramod; Sharma, Tarun; Gopal, Lingam
• Is Part Of: Asia-Pacific journal of ophthalmology. Volume 4:Issue 5(2015)
• Publication Date: 2015-09
• Subjects: Ophthalmology -- Periodicals; Eye -- Diseases -- Periodicals; Periodicals; 617.7005
• DOI: 10.1097/APO.0000000000000120
• Languages: English
• ISSNs: 0129-1653

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title>Purpose</title> <p>The aim of this study was to review the clinical profile including predisposing systemic conditions, microorganisms responsible, clinical presentation, and outcomes of endogenous endophthalmitis (EE) in South India.</p> </sec> <sec> <title>Design</title> <p>This study is a retrospective, noncomparative case series.</p> </sec> <sec> <title>Methods</title> <p>This study presents a retrospective analysis of records of patients with EE in a 10-year period.</p> </sec> <sec> <title>Results</title> <p>A total of 61 eyes of 58 patients were included in the study. Preceding systemic illness or surgery was noted in 31 patients (53.4%). No predisposing condition was found in 27 patients (46.5%). All eyes had severe diffuse EE. Culture positivity was seen in 34 of 58 patients (58.6%). Gram-positive organisms were isolated in 9 cases (15.5%), and Gram-negative organisms were isolated in 20 cases (34.5%). <italic>Pseudomonas aeruginosa</italic> (13.8%) was the most common isolate. Eleven eyes (18%) were managed medically with intravenous and intravitreal antibiotics, and 38 eyes (62.3%) also underwent vitrectomy. Eight eyes (13.1%) required repeat vitrectomy, and 12 eyes (19.7%) were eviscerated. The mean follow-up was 16.2 ± 13.9 months. Final visual acuity of 20/200 or better was seen in 29.5% eyes. A favorable outcome was noted in culture-positive patients (<italic>P</italic> = 0.03) and in patients with no predisposing causes.</p> </sec> <sec> <title>Conclusions</title> <p>This study provides information about the clinical and microbiologic profile of EE. Aggressive medical and surgical treatment can result in favorable outcomes.</p> </sec> </abstract>