A bivalent virus-like particle based vaccine induces a balanced antibody response against both enterovirus 71 and norovirus in mice. Issue 43 (26th October 2015)

• Record Type: Journal Article
• Authors: Wang, Xiaoli; Ku, Zhiqiang; Dai, Wenlong; Chen, Tan; Ye, Xiaohua; Zhang, Chao; Zhang, Yingyi; Liu, Qingwei; Jin, Xia; Huang, Zhong
• Is Part Of: Vaccine. Volume 33:Issue 43(2015)
• Page Start: 5779
• Page End: 5785
• Publication Date: 2015-10-26
• Subjects: Vaccines -- Periodicals; 615.372
• DOI: 10.1016/j.vaccine.2015.09.043
• Languages: English
• ISSNs: 0264-410X

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">A combination vaccine comprising EV71- and NoV GII.4-VLPs was formulated.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">The bivalent vaccine elicited a balanced antibody response toward both EV71 and GII.4.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">The bivalent vaccine-induced antibodies exhibited inhibitory effects on EV71 and NoV GII.4.</p> </list-item> </list> </p> </sec> </abstract>