Synthetic TRP2 long-peptide and α-galactosylceramide formulated into cationic liposomes elicit CD8+ T-cell responses and prevent tumour progression. Issue 43 (26th October 2015)

• Record Type: Journal Article
• Authors: Neumann, Silke; Young, Katie; Compton, Benji; Anderson, Regan; Painter, Gavin; Hook, Sarah
• Is Part Of: Vaccine. Volume 33:Issue 43(2015)
• Page Start: 5838
• Page End: 5844
• Publication Date: 2015-10-26
• Subjects: Vaccines -- Periodicals; 615.372
• DOI: 10.1016/j.vaccine.2015.08.083
• Languages: English
• ISSNs: 0264-410X

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">SC immunisation with liposomal α-GalCer vaccine induced cytotoxic T-cell responses.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Delayed tumour growth after IV but not SC administration of liposomal vaccine.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Optimal responses to peptide antigens require co-delivery with α-GalCer.</p> </list-item> </list> </p> </sec> </abstract>