Antimicrobial resistance in bacteria from horses: Epidemiology of antimicrobial resistance. (26th August 2015)

• Record Type: Journal Article
• Authors: Maddox, T. W.; Clegg, P. D.; Williams, N. J.; Pinchbeck, G. L.
• Is Part Of: Equine veterinary journal. Volume 47:Number 6(2015:Nov.)
• Page Start: 756
• Page End: 765
• Publication Date: 2015-08-26
• Subjects: Horses -- Diseases -- Periodicals; 636.108905
• DOI: 10.1111/evj.12471
• Languages: English
• ISSNs: 0425-1644

Abstract

<abstract abstract-type="main" id="evj12471-abs-0001"> <title>Summary</title> <p>Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections. While the epidemiology of antimicrobial resistance in bacteria from man has been studied extensively, less work has been undertaken in companion animals, particularly horses. Methicillin‐resistant <italic>Staphylococcus aureus</italic> has been identified as a cause of infections, with a low prevalence of nasal carriage by horses in the community but higher for hospitalised horses. Molecular characterisation has shown methicillin‐resistant <italic>Staphylococcus aureus</italic> strains either to be predominantly of types associated with horses or of sequence type ST398. Antimicrobial‐resistant <italic>Escherichia coli</italic> (including multidrug‐resistant and extended spectrum β‐lactamase‐producing isolates) have caused infections and been documented in faecal carriage by horses, with many significant resistance mechanisms identified. More sporadic reports and molecular characterisation exist for resistance in other bacteria such as enterococci, <italic>Salmonella</italic>, <italic> Acinetobacter</italic> and <italic>Pseudomonas</italic> species. Limited work has been undertaken evaluating risk factors and much of the epidemiology of antimicrobial resistance in bacteria from horses remains to be determined.</p> </abstract>