Plasmodium berghei ANKA infection results in exacerbated immune responses from C57BL/6 mice displaying hypothalamic obesity. Issue 2 (December 2015)

• Record Type: Journal Article
• Authors: de Carvalho, Renan Villanova Homem; Soares, Sara Malaguti Andrade; Gualberto, Ana Cristina Moura; Evangelista, Gabriela Coeli Menezes; Duque, Juliane Aparecida Marinho; Ferreira, Ana Paula; Macedo, Gilson Costa; Gameiro, Jacy
• Is Part Of: Cytokine. Volume 76:Issue 2(2015)
• Page Start: 545
• Page End: 548
• Publication Date: 2015-12
• Subjects: Cytokines -- Periodicals; 571.844
• DOI: 10.1016/j.cyto.2015.01.025
• Languages: English
• ISSNs: 1043-4666

Abstract

<abstract xml:lang="en" abstract-type="graphical" id="ab005"> <title id="st005">Graphical abstract</title> <sec> <p id="sp0005">MSG-obese mice infected with <italic>Plasmodium berghei</italic> ANKA produce high levels of pro inflammatory cytokines that could be activating leukocytes, leading to parasite elimination by itself or with other unknown mechanisms. However, this strong inflammatory process might be inducing brain damage and mice death. Dashed black arrow represents unknown mechanisms. Dashed red arrows represent hypothetical effects. <fig id="f0015" position="anchor"><graphic position="anchor" xlink:href="ark:/27927/pgkfxm1k7c" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></fig></p> </sec> </abstract>