Cigarette smoke affects IL-17A, IL-17F and IL-17 receptor expression in the lung tissue: Ex vivo and in vitro studies. Issue 2 (December 2015)

• Record Type: Journal Article
• Authors: Montalbano, Angela Marina; Riccobono, Loredana; Siena, Liboria; Chiappara, Giuseppina; Di Sano, Caterina; Anzalone, Giulia; Gagliardo, Rosalia; Ricciardolo, Fabio L.M.; Sorbello, Valentina; Pipitone, Loredana; Vitulo, Patrizio; Profita, Mirella
• Is Part Of: Cytokine. Volume 76:Issue 2(2015)
• Page Start: 391
• Page End: 402
• Publication Date: 2015-12
• Subjects: Cytokines -- Periodicals; 571.844
• DOI: 10.1016/j.cyto.2015.07.013
• Languages: English
• ISSNs: 1043-4666

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st005">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0005">IL-17A, IL-17F and the related receptor IL-17R are increased in COPD.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0010">Cigarette smoke habit affect the activity of IL-17A produced in the sub-epithelium.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0015">IL-17A rather than IL-17F activates airway epithelial cells in COPD patients.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0020">IL-17A affects epithelial cell proliferation and apoptosis during COPD.</p> </list-item> </list> </p> </sec> </abstract>