Notch signaling: An emerging therapeutic target for cancer treatment. Issue 1 (1st December 2015)

• Record Type: Journal Article
• Authors: Yuan, Xun; Wu, Hua; Xu, Hanxiao; Xiong, Huihua; Chu, Qian; Yu, Shiying; Wu, Gen Sheng; Wu, Kongming
• Is Part Of: Cancer letters. Volume 369:Issue 1(2016)
• Page Start: 20
• Page End: 27
• Publication Date: 2015-12-01
• Subjects: Cancer -- Periodicals; Neoplasms -- Periodicals; Cancer -- Périodiques; Electronic journals; 616.994
• DOI: 10.1016/j.canlet.2015.07.048
• Languages: English
• ISSNs: 0304-3835

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010">The Notch signaling pathway is commonly activated in cancer and its activation plays key role in the progress of cancer.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">Pharmacological inhibitors of this pathway can overcome chemoresistance.</p> </list-item> <list-item id="u0020"> <label></label> <p id="p0020">Notch inhibitor alone or in combination with chemotherapeutics is clinically evaluated on some cancer.</p> </list-item> </list> </p> </sec> </abstract>