Epstein–Barr virus encephalitis in a renal transplant recipient manifesting as hemorrhagic, ring‐enhancing mass lesions. Issue 5 (26th September 2015)

• Record Type: Journal Article
• Authors: Babik, J.M.; Katrak, S.; Miller, S.; Shah, M.; Chin‐Hong, P.
• Is Part Of: Transplant infectious disease. Volume 17:Issue 5(2016)
• Page Start: 744
• Page End: 750
• Publication Date: 2015-09-26
• Subjects: Transplantation of organs, tissues, etc -- Complications -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 617.01
• DOI: 10.1111/tid.12431
• Languages: English
• ISSNs: 1398-2273

Abstract

<abstract abstract-type="main" id="tid12431-abs-0001"> <title>Abstract</title> <p>Epstein–Barr virus (EBV) encephalitis has been infrequently described in immunocompromised patients. Here, we report a unique case of biopsy‐proven EBV encephalitis in a renal transplant recipient presenting with altered mental status, prominent visual disturbances, and hemorrhagic, ring‐enhancing mass lesions on magnetic resonance imaging. The patient was successfully treated with a prolonged course of antivirals. This case illustrates the difficulty in interpretation of cerebrospinal fluid EBV polymerase chain reaction assay, given the lack of specificity in immunocompromised patients.</p> </abstract>