Associations Between Mild Cognitive Impairment and Hospitalization and Readmission. Issue 9 (27th August 2015)

• Record Type: Journal Article
• Authors: Callahan, Kathryn E.; Lovato, James F.; Miller, Michael E.; Easterling, Doug; Snitz, Beth; Williamson, Jeff D.
• Is Part Of: Journal of the American Geriatrics Society. Volume 63:Issue 9(2015:Sep.)
• Page Start: 1880
• Page End: 1885
• Publication Date: 2015-08-27
• Subjects: Geriatrics -- Periodicals; 618.97
• DOI: 10.1111/jgs.13593
• Languages: English
• ISSNs: 0002-8614

Abstract

<abstract abstract-type="main" id="jgs13593-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="jgs13593-sec-0001" sec-type="section"> <title>Objectives</title> <p>To determine whether older adults with mild cognitive impairment (MCI), a condition not previously explored as a risk factor, have more hospitalizations and 30‐day readmissions than those with normal cognition.</p> </sec> <sec id="jgs13593-sec-0002" sec-type="section"> <title>Design</title> <p>Post hoc analysis of prospectively gathered data on incident hospitalization and readmission from the Ginkgo Evaluation of Memory Study (GEMS), a randomized, double‐blind, placebo‐controlled trial designed to assess the effect of <italic>Ginkgo biloba</italic> on incidence of dementia.</p> </sec> <sec id="jgs13593-sec-0003" sec-type="section"> <title>Setting</title> <p>GEMS was conducted in five academic medical centers in the United States.</p> </sec> <sec id="jgs13593-sec-0004" sec-type="section"> <title>Participants</title> <p>Community‐dwelling adults aged 75 and older with normal cognition (n = 2, 314) or MCI (n = 428) at baseline cognitive testing (N = 2, 742).</p> </sec> <sec id="jgs13593-sec-0005" sec-type="section"> <title>Measurements</title> <p>Index hospitalization and 30‐day hospital readmission, adjusted for age, sex, race, education, clinic site, trial assignment status, comorbidities, number of prescription medications, and living with an identified proxy.</p> </sec> <sec id="jgs13593-sec-0006" sec-type="section"> <title>Results</title> <p>MCI was associated with a 17% greater risk of index hospitalization than normal cognition (adjusted hazard ratio (aHR) = 1.17, 95% confidence interval (CI) = 1.02–1.34)). In participants who lived with a proxy, MCI was associated with a 39% greater risk of index hospitalization (aHR = 1.39, 95% CI = 1.17–1.66). Baseline MCI was not associated with greater odds of 30‐day hospital readmission (adjusted odds ratio = 0.90, 95% CI = 0.60–1.36).</p> </sec> <sec id="jgs13593-sec-0007" sec-type="section"> <title>Conclusion</title> <p>MCI may represent a target condition for healthcare providers to coordinate support services in an effort to reduce hospitalization and subsequent disability.</p> </sec> </abstract>