Pteropine orthoreovirus infection among out‐patients with acute upper respiratory tract infection in Malaysia. Issue 12 (28th September 2015)

• Record Type: Journal Article
• Authors: Voon, Kenny; Tan, Yeh Fong; Leong, Pooi Pooi; Teng, Cheong Lieng; Gunnasekaran, Rajasekaran; Ujang, Kamsiah; Chua, Kaw Bing; Wang, Lin‐Fa
• Is Part Of: Journal of medical virology. Volume 87:Issue 12(2015:Dec.)
• Page Start: 2149
• Page End: 2153
• Publication Date: 2015-09-28
• Subjects: Virology -- Periodicals; 616
• DOI: 10.1002/jmv.24304
• Languages: English
• ISSNs: 0146-6615

Abstract

<abstract abstract-type="main" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="jmv24304-sec-0001" sec-type="section"> <p>This study aims to assess the incidence rate of <italic>Pteropine orthreovirus</italic> (PRV) infection in patients with acute upper respiratory tract infection (URTI) in a suburban setting in Malaysia, where bats are known to be present in the neighborhood. Using molecular detection of PRVs directly from oropharyngeal swabs, our study demonstrates that PRV is among one of the common causative agents of acute URTI with cough and sore throat as the commonest presenting clinical features. Phylogenetic analysis on partial major outer and inner capsid proteins shows that these PRV strains are closely related to Melaka and Kampar viruses previously isolated in Malaysia. Further study is required to determine the public health significance of PRV infection in Southeast Asia, especially in cases where co‐infection with other pathogens may potentially lead to different clinical outcomes. <bold><italic>J. Med. Virol. 87:2149–2153, 2015</italic>.</bold> © 2015 Wiley Periodicals, Inc.</p> </sec> </abstract>