Direct Electrochemistry of Glucose Oxidase at Reduced Graphene Oxide and β‐Cyclodextrin Composite Modified Electrode and Application for Glucose Biosensing. Issue 10 (26th June 2015)

• Record Type: Journal Article
• Authors: Palanisamy, Selvakumar; Devasenathipathy, Rajkumar; Chen, Shen‐Ming; Ajmal Ali, M.; Karuppiah, Chelladurai; Balakumar, V.; Prakash, P.; Elshikh, Mohamed S.; Al‐Hemaid, Fahad M. A.
• Is Part Of: Electroanalysis. Volume 27:Issue 10(2015:Oct.)
• Page Start: 2412
• Page End: 2420
• Publication Date: 2015-06-26
• Subjects: Electrochemical analysis -- Periodicals; Chemistry, Analytical -- Periodicals; Electrochemistry -- Periodicals; 543.4
• DOI: 10.1002/elan.201500150
• Languages: English
• ISSNs: 1040-0397

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A simple glucose biosensor has been developed based on direct electrochemistry of glucose oxidase (GOx) immobilized on the reduced graphene oxide (RGO) and β‐cyclodextrin (CD) composite. A well‐defined redox couple of GOx appears with a formal potential of ∼−0.459 V at RGO/CD composite. A heterogeneous electron transfer rate constant (<italic>K</italic>_s) has been calculated for GOx at RGO/CD as 3.8 s⁻¹. The fabricated biosensor displays a wide response to glucose in the linear concentrations range from 50 µM to 3.0 mM. The sensitivity and limit of detection of the biosensor is estimated as 59.74 µA mM⁻¹ cm⁻² and 12 µM, respectively.</p> </abstract>