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5d, a novel analogue of 3-n-butylphthalide, protects brains against nervous injury induced by ischemia/reperfusion through Akt/Nrf2/NOX4 signaling pathway1. Issue 85 (16th September 2015)
Record Type:
Journal Article
Title:
5d, a novel analogue of 3-n-butylphthalide, protects brains against nervous injury induced by ischemia/reperfusion through Akt/Nrf2/NOX4 signaling pathway1. Issue 85 (16th September 2015)
Main Title:
5d, a novel analogue of 3-n-butylphthalide, protects brains against nervous injury induced by ischemia/reperfusion through Akt/Nrf2/NOX4 signaling pathway1
<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj2rwc5bc0" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /> <bold>5d</bold>, a novel analogue of 3-<italic>n</italic>-butylphthalide, decreases NADPH oxidase activity by the activation of Nrf2 through PI3K/Akt signaling pathway after I/R and may be an effective candidate for the treatment of ischemic stroke.</p> </abstract>