Different Clinical Presentations of Hyperlipidemic Acute Pancreatitis. Issue 7 (October 2015)

• Record Type: Journal Article
• Authors: Yin, Guojian; Cang, Xiaofeng; Yu, Ge; Hu, Guoyong; Ni, Jianbo; Xiong, Jie; Hu, Yanling; Xing, Miao; Chen, Congying; Huang, Yinshi; Tang, Maochun; Zhao, Yan; Cheng, Guilian; Wan, Rong; Wang, Shaofeng; Wang, Xingpeng
• Is Part Of: Pancreas. Volume 44:Issue 7(2015)
• Publication Date: 2015-10
• Subjects: Pancreas -- Diseases -- Periodicals; Pancreas -- Periodicals; Neuroendocrine tumors -- Periodicals; 616.37005
• DOI: 10.1097/MPA.0000000000000403
• Languages: English
• ISSNs: 0885-3177

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title>Objectives</title> <p>The goal of this study was to summarize the clinical features of hyperlipidemic acute pancreatitis (HLAP), and help clinicians understand the characteristic presentations of HLAP.</p> </sec> <sec> <title>Methods</title> <p>From July 2009 to June 2013, 1073 cases of acute pancreatitis were retrospectively assessed. The clinical characteristics of HLAP and non-HLAP were statistically analyzed.</p> </sec> <sec> <title>Results</title> <p>The etiologic ratio of HLAP in acute pancreatitis rose from 13% in 2009 to 25.6% in 2013. Diabetes mellitus, fatty liver, and acute pancreatitis recurrence were positively correlated with HLAP, and female sex, age (&gt;60 years), and alkaline phosphatase level were negatively correlated with HLAP. The diagnostic accuracy of amylase in HLAP was only 40.38%, compared with lipase (91.83%). Different cutoff points of serum triglyceride on day 1 (5.33 mmol/L), day 2 (2.77 mmol/L), and day 3 (2.18 mmol/L) could be used to obtain an accurate diagnosis of HLAP. Higher incidences of acute peripancreatic fluid collection, renal failure, and severe acute pancreatitis were also observed in patients with HLAP.</p> </sec> <sec> <title>Conclusions</title> <p>Different clinical presentations of HLAP should be applied to be distinguished from non-HLAP in the clinic.</p> </sec> </abstract>