A non-destructive test to assess the axial heterogeneity of in situ modified monoliths for HPLC. Issue 17 (7th September 2015)

• Record Type: Journal Article
• Authors: Bassanese, Danielle N.; Soliven, Arianne; Conlan, Xavier A.; Shalliker, R. Andrew; Barnett, Neil W.; Stevenson, Paul G.
• Is Part Of: Analytical methods. Volume 7:Issue 17(2015)
• Page Start: 7177
• Page End: 7185
• Publication Date: 2015-09-07
• Subjects: Chemistry, Analytic -- Periodicals; Analytical biochemistry -- Periodicals; Chemical laboratories -- Standards -- Periodicals; 543.1905
• DOI: 10.1039/c4ay02812k
• Languages: English
• ISSNs: 1759-9660

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj2rw59h0r" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />A multi-location peak parking protocol was developed for a non-destructive assessment of the axial heterogeneity of <italic>in situ</italic> modified monoliths. This was tested on a column with a surface coverage density gradient along the length of the monolithic rod. Qualitative changes in band broadening were observed and were consistent with theoretical studies.</p> </abstract>