<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj2xwv4d7h" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />The combination of an amphiphilic and a hydrophobic reactive prepolymer promotes the self-stratification of the whole PUUa NP by hydrophobic interactions.</p> </abstract>