Alkoxide coordination of iron(iii) protoporphyrin IX by antimalarial quinoline methanols: a key interaction observed in the solid-state and solution1. Issue 38 (14th October 2015)

• Record Type: Journal Article
• Authors: Gildenhuys, Johandie; Sammy, Chandre J.; Müller, Ronel; Streltsov, Victor A.; le Roex, Tanya; Kuter, David; de Villiers, Katherine A.
• Is Part Of: Dalton transactions. Volume 44:Issue 38(2015)
• Page Start: 16767
• Page End: 16777
• Publication Date: 2015-10-14
• Subjects: Chemistry, Inorganic -- Periodicals; Chemistry, Physical and theoretical -- Periodicals; Chemistry, Inorganic -- Periodicals; 546.05
• DOI: 10.1039/c5dt02671g
• Languages: English
• ISSNs: 1477-9226

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj2xvqqwjq" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Quinoline methanol antimalarial drugs coordinate to ferriprotoporphyrin IX <italic>via</italic> their alkoxide oxygen atom in both the solid-state and non-aqueous solution.</p> </abstract>