Design of CID-cleavable protein cross-linkers: identical mass modifications for simpler sequence analysis1. Issue 38 (14th October 2015)

• Record Type: Journal Article
• Authors: Kandur, Wynne V.; Kao, Athit; Vellucci, Danielle; Huang, Lan; Rychnovsky, Scott D.
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 38(2015)
• Page Start: 9793
• Page End: 9807
• Publication Date: 2015-10-14
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob01410g
• Languages: English
• ISSNs: 1477-0520

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj2xvnh1sv" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Cross-linking Mass Spectrometry (XL-MS) is a powerful tool for studying protein-protein interactions. New developments in MS-cleavable linkers further facilitate unambiguous identification of low abundance cross-linked peptides.</p> </abstract>