Developmental considerations for ethanolates with regard to stability and physicochemical characterization of efonidipine hydrochloride ethanolate1. Issue 38 (14th October 2015)

• Record Type: Journal Article
• Authors: Otsuka, M.; Maeno, Y.; Fukami, T.; Inoue, M.; Tagami, T.; Ozeki, T.
• Is Part Of: CrystEngComm. Volume 17:Issue 38(2015)
• Page Start: 7430
• Page End: 7436
• Publication Date: 2015-10-14
• Subjects: Crystals -- Periodicals; Crystal growth -- Periodicals; Crystallography -- Periodicals; Cristaux -- Périodiques; Cristaux -- Croissance -- Périodiques; Cristallographie -- Périodiques; 548
• DOI: 10.1039/c5ce00751h
• Languages: English
• ISSNs: 1466-8033

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj2xvm5gb4" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Efonidipine hydrochloride ethanolate arranges the chloride ion within a basket-type conformation. This distinctive crystal structure would contribute to the improvement of the API's thermal stability.</p> </abstract>