Chicken IgY facilitates allergic airway inflammation in a chemical-induced murine asthma model by potentiating IL-4 release. Issue 1 (19th November 2015)

• Record Type: Journal Article
• Authors: Yao, Lihong; Zhao, Haijin; Tang, Haixiong; Song, Jiafu; Dong, Hangming; Zou, Fei; Cai, Shaoxi
• Is Part Of: Toxicology letters. Volume 239:Issue 1(2015)
• Page Start: 22
• Page End: 31
• Publication Date: 2015-11-19
• Subjects: Toxicology -- Periodicals; 363.179
• DOI: 10.1016/j.toxlet.2015.08.1108
• Languages: English
• ISSNs: 0378-4274

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0035"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Chicken IgY anti-HMGB1 antibody exacerbates TDI-induced allergic airway inflammation.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">IgY aggravates the asthmatic reaction and anti-HMGB1 counteracts the effects of IgY.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">It is IgY that facilitates TDI-induced allergic airway inflammation by promoting the release of IL-4.</p> </list-item> </list> </p> </sec> </abstract>