Subarachnoid hemorrhage due to aneurysm rupture in a young woman with Alagille syndrome – A rare cause of sudden death. Issue 5 (September 2015)

• Record Type: Journal Article
• Authors: Doberentz, E.; Kuchelmeister, K.; Madea, B.
• Is Part Of: Legal medicine. Volume 17:Issue 5(2015:Sep.)
• Page Start: 309
• Page End: 312
• Publication Date: 2015-09
• Subjects: Medical jurisprudence -- Periodicals; Forensic Medicine -- Periodicals; Médecine légale -- Périodiques; Medical jurisprudence; Periodicals; 614.1
• DOI: 10.1016/j.legalmed.2015.03.004
• Languages: English
• ISSNs: 1344-6223

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab015"> <title id="st055">Highlights</title> <sec> <p id="sp0055"> <list id="l0010"> <list-item id="o0045"> <label></label> <p id="p0130">The Alagille syndrome is a rare, autosomal dominant inherited disease which is mainly characterized by a reduction of the number of bile ducts leading to cholestasis.</p> </list-item> <list-item id="o0055"> <label></label> <p id="p0140">Several other organs may be effected.</p> </list-item> <list-item id="o0060"> <label></label> <p id="p0145">In the presented case a 25 year old woman with Alagille syndrome who had liver transplantation in the age of 7 and 8 years died suddenly and unexpectedly.</p> </list-item> <list-item id="o0065"> <label></label> <p id="p0150">Cause of death was a subarachnoidal hemorrhage due to rupture of an undiagnosed aneurysm of the basilary artery.</p> </list-item> <list-item id="o0070"> <label></label> <p id="p0155">Due to the high rate of vascular complications in patients with Alagille syndrome a vascular screening may be necessary.</p> </list-item> </list> </p> </sec> </abstract>