Predictive and prognostic biomarkers for neoadjuvant chemoradiotherapy in locally advanced rectal cancer. Issue 1 (October 2015)

• Record Type: Journal Article
• Authors: Lim, S.H.; Chua, W.; Henderson, C.; Ng, W.; Shin, J.-S.; Chantrill, L.; Asghari, R.; Lee, C.S.; Spring, K.J.; de Souza, P.
• Is Part Of: Critical reviews in oncology/hematology. Volume 96:Issue 1(2015)
• Page Start: 67
• Page End: 80
• Publication Date: 2015-10
• Subjects: Oncology -- Periodicals; Hematology -- Periodicals; 616.994
• DOI: 10.1016/j.critrevonc.2015.05.003
• Languages: English
• ISSNs: 1040-8428

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Biomarkers are needed to assess treatment response in locally advanced rectal cancer.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Experimental markers include proteins involved in cell proliferation and apoptosis.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">There is no one biomarker currently that has robust clinical utility.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Microarrays that can interrogate a tumour for multiple candidates have potential.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">Circulating tumour cells or nucleic acids are likely the way forward.</p> </list-item> </list> </p> </sec> </abstract>