Carbon Nanospheres: Tunable Luminescent Carbon Nanospheres with Well‐Defined Nanoscale Chemistry for Synchronized Imaging and Therapy (Small 36/2015). Issue 36 (September 2015)

• Record Type: Journal Article
• Authors: Mukherjee, Prabuddha; Misra, Santosh K.; Gryka, Mark C.; Chang, Huei‐Huei; Tiwari, Saumya; Wilson, William L.; Scott, John W.; Bhargava, Rohit; Pan, Dipanjan
• Is Part Of: Small. Volume 11:Issue 36(2015)
• Page Start: 4796
• Page End: 4796
• Publication Date: 2015-09
• Subjects: Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.201570224
• Languages: English
• ISSNs: 1613-6810

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="smll201570224-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Drug (PTX)‐loaded luminescent carbon nanoparticles (LCNs) are passivated with a thermoresponsive polymer (PNIPAM) inside melanoma cells. On page 4691, R. Bhargava, D. Pan, and co‐workers acquire such images using confocal fluorescence techniques. A representative cartoon of the nanoparticles is shown in black, where the white and the green shells represent the anti‐cancer drug (PTX: molecular structure shown) and the PNIPAM coating, respectively. The cells, upon internalizing the particles under physiological conditions, trigger the delivery of drugs contained in them. <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgj2qk8qj2d" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></p> </abstract>