The Manchester Uveitis Clinic: The First 3000 Patients—Epidemiology and Casemix. (April 2015)

• Record Type: Journal Article
• Authors: Jones, Nicholas P.
• Is Part Of: Ocular immunology and inflammation. Volume 23:Number 2(2015)
• Page Start: 118
• Page End: 126
• Publication Date: 2015-04
• Subjects: Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.3109/09273948.2013.855799
• Languages: English
• ISSNs: 0927-3948

Abstract

<abstract> <title>Abstract</title> <p> <italic>Purpose</italic>: To demonstrate the demography, anatomical, and diagnostic classification of patients with uveitis attending the Manchester Uveitis Clinic (MUC), a specialist uveitis clinic in the northwest of England, UK.</p> <p> <italic>Methods</italic>: Retrospective retrieval of data on a computerized database incorporating all new referrals to MUC from 1991 to 2013.</p> <p> <italic>Results</italic>: A total of 3000 new patients with uveitis were seen during a 22-year period. The anatomical types seen were anterior 46%; intermediate 11.1%; posterior 21.8%; and panuveitis 21.1%. The most common diagnoses were Fuchs heterochromic uveitis (11.5% of total), sarcoidosis-related uveitis (9.7%), idiopathic intermediate uveitis (7.9%), idiopathic acute anterior uveitis (7.0%), and toxoplasmosis (6.9%). Syphilis and tuberculosis-associated uveitis increased markedly in frequency during the study period.</p> <p> <italic>Conclusions</italic>: The uveitis casemix in this region reflects a predominantly white Caucasian population in a temperate country, but with changing characteristics owing to increasing immigration, enhanced diagnostic techniques, changes in referral pattern, and some real changes in disease incidence.</p> </abstract>