Optimizing Wnt-3a and R-spondin1 concentrations for stem cell renewal and differentiation in intestinal organoids using a gradient-forming microdevice1. Issue 91 (9th October 2015)

• Record Type: Journal Article
• Authors: Ahmad, Asad A.; Wang, Yuli; Sims, Christopher E.; Magness, Scott T.; Allbritton, Nancy L.
• Is Part Of: RSC advances. Volume 5:Issue 91(2015)
• Page Start: 74881
• Page End: 74891
• Publication Date: 2015-10-09
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c5ra14923a
• Languages: English
• ISSNs: 2046-2069

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj2qrrtk5c" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />A gradient-generating device assayed the impact of Wnt-3a and R-spondin1 on colonoids identifying concentrations required to yield a physiologically-relevant epithelium.</p> </abstract>