C5-substituted pyrido[2, 3-d]pyrimidin-7-ones as highly specific kinase inhibitors targeting the clinical resistance-related EGFRT790M mutant1. Issue 9 (2nd September 2015) - Xu, Tianfeng
Abstract C5-substituted pyrido[2, 3-d]pyrimidin-7-ones were discovered as highly potent and specific inhibitors targeting the clinical resistance-related EGFRL858R/T790M mutant.