An optimized polyamine moiety boosts the potency of human type II topoisomerase poisons as quantified by comparative analysis centered on the clinical candidate F145121. Issue 76 (10th October 2015)

Record Type:
Journal Article
Title:
An optimized polyamine moiety boosts the potency of human type II topoisomerase poisons as quantified by comparative analysis centered on the clinical candidate F145121. Issue 76 (10th October 2015)
Main Title:
An optimized polyamine moiety boosts the potency of human type II topoisomerase poisons as quantified by comparative analysis centered on the clinical candidate F145121
Authors:
Palermo, Giulia
Minniti, Elirosa
Greco, Maria Laura
Riccardi, Laura
Simoni, Elena
Convertino, Marino
Marchetti, Chiara
Rosini, Michela
Sissi, Claudia
Minarini, Anna
De Vivo, Marco
Abstract:
<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj2qrkjr5v" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Computational–experimental analyses explain F14512's boosted potency as a topoII poison.</p> </abstract>
Is Part Of:
Chemical communications. Volume 51:Issue 76(2015)
Journal:
Chemical communications
Issue:
Volume 51:Issue 76(2015)
Issue Display:
Volume 51, Issue 76 (2015)
Year:
2015
Volume:
51
Issue:
76
Issue Sort Value:
2015-0051-0076-0000
Page Start:
14310
Page End:
14313
Publication Date:
2015-10-10
Subjects:
Chemistry -- Periodicals
540
Journal URLs:
http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗
DOI:
10.1039/c5cc05065k ↗
Languages:
English
ISSNs:
1359-7345
Deposit Type:
Legaldeposit
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗
Physical Locations:
British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store
Ingest File:
4116.xml