Cobalt(III) Complexes of D‐Galactosylamine1. Issue 11 (14th July 2015)

• Record Type: Journal Article
• Authors: Lindner, Leonie; Klüfers, Peter
• Is Part Of: Zeitschrift für anorganische und allgemeine Chemie. Volume 641:Issue 11(2015)
• Page Start: 1869
• Page End: 1873
• Publication Date: 2015-07-14
• Subjects: Chemistry, Inorganic -- Periodicals; Chemistry -- Periodicals; 540
• DOI: 10.1002/zaac.201500224
• Languages: English
• ISSNs: 0044-2313

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The β‐pyranose isomer of <sc>D</sc>‐galactosylamine (<bold>1</bold>) formed complexes with three different cobalt(III) fragments. Crystals containing the dication [Co(tren)(β‐<sc>D</sc>‐Gal<italic>p</italic>1N2H_–1‐κ²<italic>N</italic>¹, <italic>O</italic>²)]²⁺ (<bold>3</bold>) showed coordination through the anomeric amino group (N1) and the deprotonated hydroxy group (O2) of the ⁴<italic>C</italic>₁ β‐pyranose form, which is also the major isomer of free galactosylamine. The cationic complexes [Co(<italic>fac</italic>‐dien)(β‐<sc>D</sc>‐Gal<italic>p</italic>1N2H_–1‐κ²<italic>N</italic>¹, <italic>O</italic>²)]²⁺ (<bold>4</bold>) and [Co(phen)₂(β‐<sc>D</sc>‐Gal<italic>p</italic>1N2H_–1‐κ²<italic>N</italic>¹, <italic>O</italic>²)]²⁺ (<bold>5</bold>) were analysed by NMR spectroscopy and showed the same coordination mode as <bold>3</bold>. In terms of available ligand isomers it was shown that <bold>1</bold> exhibits an anomeric equilibrium in solution of both pyranose and both furanose forms as is typical for the parent glycose, galactose.</p> </abstract>