Translocation of positively and negatively charged polystyrene nanoparticles in an in vitro placental model. Issue 7 (October 2015)

• Record Type: Journal Article
• Authors: Kloet, Samantha K.; Walczak, Agata P.; Louisse, Jochem; van den Berg, Hans H.J.; Bouwmeester, Hans; Tromp, Peter; Fokkink, Remco G.; Rietjens, Ivonne M.C.M.
• Is Part Of: Toxicology in vitro. Volume 29:Issue 7(2015)
• Page Start: 1701
• Page End: 1710
• Publication Date: 2015-10
• Subjects: Toxicity testing -- In vitro -- Periodicals; Toxicology -- Periodicals; 615.9
• DOI: 10.1016/j.tiv.2015.07.003
• Languages: English
• ISSNs: 0887-2333

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st005">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0005">Polystyrene nanoparticle translocation was studied in a BeWo b30 transwell model.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0010">One positively and two negatively charged polystyrene nanoparticles were tested.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0015">The results reveal limited translocation of PS-NPs across the BeWo cell layer.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0020">Translocation of PS-NPs was not related to charge.</p> </list-item> <list-item id="o0025"> <label></label> <p id="p0025">The BeWo b30 model can be a screening method to set priorities for further testing.</p> </list-item> </list> </p> </sec> </abstract>