Multiwalled carbon nanotube buckypaper induces cell cycle arrest and apoptosis in human leukemia cell lines through modulation of AKT and MAPK signaling pathways. Issue 7 (October 2015)

• Record Type: Journal Article
• Authors: Dinicola, Simona; Masiello, Maria Grazia; Proietti, Sara; Coluccia, Pierpaolo; Fabrizi, Gianmarco; Palombo, Alessandro; Micciulla, Federico; Bistarelli, Silvia; Ricci, Giulia; Catizone, Angela; De Toma, Giorgio; Bizzarri, Mariano; Bellucci, Stefano; Cucina, Alessandra
• Is Part Of: Toxicology in vitro. Volume 29:Issue 7(2015)
• Page Start: 1298
• Page End: 1308
• Publication Date: 2015-10
• Subjects: Toxicity testing -- In vitro -- Periodicals; Toxicology -- Periodicals; 615.9
• DOI: 10.1016/j.tiv.2015.05.006
• Languages: English
• ISSNs: 0887-2333

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st005">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0005">BP decreased cell proliferation and increased apoptosis in leukemia cell lines.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0010">BP induced an arrest in G0/G1 phase of cell cycle with cyclin expression reduction.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0015">BP-mediated apoptosis was not mediated by ROS production.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0020">AKT and MAPK signaling pathways were involved in BP effects on leukemia cells.</p> </list-item> </list> </p> </sec> </abstract>