Insights into IL-23 biology: From structure to function. Issue 5 (October 2015)

• Record Type: Journal Article
• Authors: Floss, Doreen M.; Schröder, Jutta; Franke, Manuel; Scheller, Jürgen
• Is Part Of: Cytokine & growth factor reviews. Volume 26:Issue 5(2015)
• Page Start: 569
• Page End: 578
• Publication Date: 2015-10
• Subjects: Cytokines -- Periodicals; 571.84
• DOI: 10.1016/j.cytogfr.2015.07.005
• Languages: English
• ISSNs: 1359-6101

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Interleukin (IL-)23 is a central cytokine controlling T_H17 development.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Overshooting IL-23 signaling contribute to autoimmune diseases.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">IL-23 is a member of the IL-12-type cytokine family and consists of IL-23p19 and p40.</p> </list-item> <list-item id="lsti7015"> <label></label> <p id="par6015">IL-23 triggers heterodimerization of IL-12Rβ1 and the IL-23R.</p> </list-item> </list> </p> </sec> </abstract>