Ovarian cancer in BRCA1/2 mutation carriers: The impact of mutation position and family history on the cancer risk. Issue 2 (October 2015)

• Record Type: Journal Article
• Authors: Teixeira, Natalia; Mourits, Marian J.E.; Vos, Janet R.; Kolk, Dorina M.van der; Jansen, Liesbeth; Oosterwijk, Jan C.; Bock, Geertruida H.de
• Is Part Of: Maturitas. Volume 82:Issue 2(2015:Oct.)
• Page Start: 197
• Page End: 202
• Publication Date: 2015-10
• Subjects: Climacteric -- Periodicals; Menopause -- Periodicals; Climacteric -- Periodicals; Geriatrics -- Periodicals; Menopause -- Periodicals; Middle Aged -- Periodicals; Climatère -- Périodiques; Ménopause -- Périodiques; Climacterium; Climacteric; Menopause; Electronic journals; Periodicals; 612.66
• DOI: 10.1016/j.maturitas.2015.07.001
• Languages: English
• ISSNs: 0378-5122

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0040"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">The impact of mutation position and family history on ovarian cancer (OC) risks was assessed.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">In <italic>BRCA1</italic> families women with a mutation within the OCCR region have higher OC risks.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">In <italic>BRCA2</italic> families, mutation position did not significantly affect the OC risk.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">In <italic>BRCA2</italic> families, a family history including only OC presented a strong impact on OC risk.</p> </list-item> </list> </p> </sec> </abstract>