Adherence and future discontinuation of tyrosine kinase inhibitors in chronic phase chronic myeloid leukemia. A patient-based survey on 1133 patients. Issue 10 (October 2015)

• Record Type: Journal Article
• Authors: Breccia, Massimo; Efficace, Fabio; Sica, Simona; Abruzzese, Elisabetta; Cedrone, Michele; Turri, Diamante; Gobbi, Marco; Carella, Angelo Michele; Gozzini, Antonella; Usala, Emilio; Cavazzini, Francesco; Danise, Paolo; Tiribelli, Mario; Binotto, Gianni; Pregno, Patrizia; Bocchia, Monica; Gaidano, Gianluca; Crugnola, Monica; Bonifacio, Massimiliano; Avanzini, Paolo; Celesti, Francesca; Guella, Anna; Martino, Bruno; Annunziata, Mario; Luciano, Luigiana; Stagno, Fabio; Vallisa, Daniele; Pungolino, Esther; Iurlo, Alessandra; Rambaldi, Alessandro; Nardiello, Ida; Orlandi, Esther; Gambacorti-Passerini, Carlo; Alimena, Giuliana;
• Is Part Of: Leukemia research. Volume 39:Issue 10(2015:Oct.)
• Page Start: 1055
• Page End: 1059
• Publication Date: 2015-10
• Subjects: Leukemia -- Periodicals; Leukemia -- Periodicals; Leucémie -- Périodiques; Leukemia; Periodicals; Electronic journals; Electronic journals; 616.9941905
• DOI: 10.1016/j.leukres.2015.07.004
• Languages: English
• ISSNs: 0145-2126

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">In CML patients, social support, psychological and subjective perceptions could influence adherence.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Based on patient's survey, high rate of adherence to TKIs has been reported.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">The majority of patients would like to discuss more about discomfort, anxiety and fear of the future.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Fifty-five percent of patients did not take the drug for less than 3 days a month.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">Forty-nine percent of patients wouldn't interrupt the therapy due to fear of losing all the results achieved.</p> </list-item> </list> </p> </sec> </abstract>