GM-CSF: An immune modulatory cytokine that can suppress autoimmunity. Issue 2 (October 2015)

• Record Type: Journal Article
• Authors: Bhattacharya, Palash; Thiruppathi, Muthusamy; Elshabrawy, Hatem A.; Alharshawi, Khaled; Kumar, Prabhakaran; Prabhakar, Bellur S.
• Is Part Of: Cytokine. Volume 75:Issue 2(2015)
• Page Start: 261
• Page End: 271
• Publication Date: 2015-10
• Subjects: Cytokines -- Periodicals; 571.844
• DOI: 10.1016/j.cyto.2015.05.030
• Languages: English
• ISSNs: 1043-4666

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st005">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0005">GM-CSF is an established growth and differentiation factor for multiple cell lineages.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0010">The role of GM-CSF in steady state myelopoiesis appears to be redundant.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0015">GM-CSF has an additional role in the modulation of myeloid cell functions.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0020">Immune modulatory role of GM-CSF determines the outcome of many autoimmune diseases.</p> </list-item> <list-item id="o0025"> <label></label> <p id="p0025">We review literature to discuss of the role of GM-CSF in immune tolerance.</p> </list-item> </list> </p> </sec> </abstract>