Infliximab and etanercept have distinct actions but similar effects on cytokine profiles in rheumatoid arthritis. Issue 2 (October 2015)

• Record Type: Journal Article
• Authors: Takeshita, Masaru; Suzuki, Katsuya; Kikuchi, Jun; Izumi, Keisuke; Kurasawa, Takahiko; Yoshimoto, Keiko; Amano, Koichi; Takeuchi, Tsutomu
• Is Part Of: Cytokine. Volume 75:Issue 2(2015)
• Page Start: 222
• Page End: 227
• Publication Date: 2015-10
• Subjects: Cytokines -- Periodicals; 571.844
• DOI: 10.1016/j.cyto.2015.04.011
• Languages: English
• ISSNs: 1043-4666

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st005">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0005">We compared serum cytokines in RA patients treated by infliximab and etanercept.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0010">Serum IL-6 is decreased by etanercept and infliximab treatment to the same degree.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0015">Serum IFNγ and TNFβ are increased by infliximab treatment.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0020">IFNγ increase is a distinctive feature of the inefficacy of infliximab treatment.</p> </list-item> </list> </p> </sec> </abstract>