CXCL7-induced macrophage infiltration in lung tumor is independent of CXCR2 expression. Issue 2 (October 2015)

• Record Type: Journal Article
• Authors: Unver, Nese; Esendagli, Gunes; Yilmaz, Guldal; Guc, Dicle
• Is Part Of: Cytokine. Volume 75:Issue 2(2015)
• Page Start: 330
• Page End: 337
• Publication Date: 2015-10
• Subjects: Cytokines -- Periodicals; 571.844
• DOI: 10.1016/j.cyto.2015.07.018
• Languages: English
• ISSNs: 1043-4666

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st005">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0005">Macrophage infiltration was increased in CXCL7-overexpressing LLC tumors.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0010">Increased macrophage infiltration was independent of CXC receptor 2 (CXCR2).</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0015">The overexpression of the CXCL7 chemokine induced M2-type macrophage infiltration.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0020">Accelerated tumor growth was detected in CXCL7-overexpressing tumors.</p> </list-item> <list-item id="o0025"> <label></label> <p id="p0025">The infiltration of T-cell subsets did not change in CXCL7-LLC tumors.</p> </list-item> </list> </p> </sec> </abstract>