Expression of Pannexin3 in human odontoblast-like cells and its hemichannel function in mediating ATP release. Issue 10 (October 2015)

• Record Type: Journal Article
• Authors: Fu, Dongjie; Song, Fangfang; Sun, Hualing; Pei, Dandan; Wang, Yake; Lei, Jinmei; Huang, Cui
• Is Part Of: Archives of oral biology. Volume 60:Issue 10(2015:Oct.)
• Page Start: 1510
• Page End: 1516
• Publication Date: 2015-10
• Subjects: Mouth -- Periodicals; Mouth -- Diseases -- Periodicals; Dentistry -- Periodicals; Electronic journals; 617.6005
• DOI: 10.1016/j.archoralbio.2015.07.005
• Languages: English
• ISSNs: 0003-9969

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0035"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Pannexin3 mRNA and protein are detected in the human dental pulp tissue and hOBs.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">To examine the function of Panx3, Panx3 over expression and knockdown hOBs were established.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">In presence of cold stimulus, ATP was released from hOBs into extracellular space.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Panx3 hemichannel is one of the major ATP release channels in hOBs.</p> </list-item> </list> </p> </sec> </abstract>