Lanthanide Luminescence Modulation by Cation–π Interaction in a Bioinspired Scaffold: Selective Detection of Copper(I). (29th July 2015)

• Record Type: Journal Article
• Authors: Isaac, Manon; Denisov, Sergey A.; Roux, Amandine; Imbert, Daniel; Jonusauskas, Gediminas; McClenaghan, Nathan D.; Sénèque, Olivier
• Is Part Of: Angewandte Chemie. Volume 127:Number 39(2015)
• Page Start: 11615
• Page End: 11618
• Publication Date: 2015-07-29
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/ange.201505733
• Languages: English
• ISSNs: 0044-8249

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A prototype luminescent turn‐on probe for Cu⁺ (and Ag⁺) is described, harnessing a selective binding site (log K_ass=9.4 and 7.3 for Cu⁺ and Ag⁺, respectively) based on the coordinating environment of the bacterial metallo‐chaperone CusF, integrated with a terbium‐ion‐signaling moiety. Cation–π interactions were shown to enhance tryptophan triplet population, which subsequently sensitized, on the microsecond timescale, the long‐lived terbium emission, offering a novel approach in bioinspired chemosensor design.</p> </abstract>