Increased Decline in Pulmonary Function Among Employees in Norwegian Smelters Reporting Work-Related Asthma-Like Symptoms. Issue 9 (September 2015)

• Record Type: Journal Article
• Authors: Søyseth, Vidar; Johnsen, Helle Laier; Henneberger, Paul K.; Kongerud, Johny
• Is Part Of: Journal of occupational and environmental medicine. Volume 57:Issue 9(2015)
• Publication Date: 2015-09
• Subjects: Medicine, Industrial -- Periodicals; Environmental health -- Periodicals; Occupational Medicine -- Periodicals; Environmental Medicine -- Periodicals; Environmental health; Medicine, Industrial; Periodicals; Electronic journals; 616.9803
• DOI: 10.1097/JOM.0000000000000518
• Languages: English
• ISSNs: 1076-2752

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title>Objective:</title> <p>To investigate associations between work-related asthma-like symptoms (WASTH) and annual pulmonary function decline among employees of 18 Norwegian smelters.</p> </sec> <sec> <title>Methods:</title> <p>A 5-year longitudinal study in which WASTH was defined as a combination of dyspnea and wheezing that improved on rest days and vacation.</p> </sec> <sec> <title>Results:</title> <p>A total of 12, 966 spirometry examinations were performed in 3084 employees. Crude annual decline in forced expiratory volume in 1 second (FEV₁) (dFEV₁) was 32.9 mL/yr (95% confidence interval, 30.5 to 35.3), and crude annual decline in forced vital capacity (FVC) (dFVC) was 40.9 mL/yr (37.8 to 43.9). After adjustment for relevant covariates, employees reporting WASTH showed higher dFEV₁ by 16.0 m:/yr (3.4 to 28.6) and higher dFVC by 20.5 mL/yr (6.0 to 35.0) compared with employees not reporting WASTH.</p> </sec> <sec> <title>Conclusion:</title> <p>Work-related asthma-like symptom was associated with greater annual declines in FEV₁ and FVC, indicating a restrictive pattern.</p> </sec> </abstract>