Utility Analysis of Vision-related Quality of Life in Patients With Glaucoma and Different Perceptions from Ophthalmologists. Issue 7 (September 2015)

• Record Type: Journal Article
• Authors: Zhang, Shaodan; Liang, Yuanbo; Chen, Yanyun; Musch, David C.; Zhang, Chun; Wang, Ningli
• Is Part Of: Journal of glaucoma. Volume 24:Issue 7(2015:Sep.)
• Publication Date: 2015-09
• Subjects: Glaucoma -- Periodicals; 617.741005
• DOI: 10.1097/IJG.0000000000000056
• Languages: English
• ISSNs: 1057-0829

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title>Purpose:</title> <p>To evaluate patient-perceived quality of life with glaucoma and to assess whether ophthalmologists fully appreciate patients' perceptions through utility analysis.</p> </sec> <sec> <title>Patients and Methods:</title> <p>Utility values were obtained from 87 glaucoma patients by linear rating scale (RS), standard gamble for blindness (SG), and time trade-off (TTO) methods. Identical questionnaires were delivered to ophthalmologists (n=26) at the same center, who were asked to assume they had mild (MD in better-seeing eye ≥−6 dB) or moderate to severe (MD in better-seeing eye <−6 dB) glaucoma. Responses from patients and ophthalmologists were compared.</p> </sec> <sec> <title>Results:</title> <p>Patients with mild glaucoma gave a utility value of 0.70±0.14, 0.85±0.14, and 0.77±0.14 with RS, SG, and TTO method, respectively. Those with moderate to severe glaucoma generated corresponding utilities of 0.56±0.20, 0.75±0.20, and 0.78±0.11. RS and SG utilities were affected by disease severity and history of glaucoma surgery, whereas TTO utility was mainly related with education level and employment status of the patients. Ophthalmologists reported higher utility values than their patients when mild glaucoma was assumed (0.81±0.14, 0.96±0.05, and 0.95±0.05 for RS, SG, and TTO methods, respectively; <italic>P</italic><0.05). Given the scenario of moderate to severe glaucoma, ophthalmologists gave significantly lower RS (0.35±0.21, <italic>P</italic><0.001), but similar SG (0.74±0.27, <italic>P</italic>=0.84) and TTO (0.82±0.13, <italic>P</italic>=0.40) utility values, than the patients.</p> </sec> <sec> <title>Conclusions:</title> <p>Utility values are considerably decreased in Chinese patients with glaucoma. Ophthalmologists tend to substantially underestimate the impact of mild glaucoma on patients' quality of life. Better understanding patients' perceptions of glaucoma would be helpful for the establishment of shared decision making and patient-centered care.</p> </sec> </abstract>