Quinoxaline: a new directing group for ortho C–H alkenylation / intramolecular ortho C–H cycloamination under open air leading to bioactive polynuclear N-heteroarenes1. Issue 86 (18th September 2015)

• Record Type: Journal Article
• Authors: Sunke, Rajnikanth; Kumar, Vimal; Venkat Shivaji Ramarao, E. V.; Bankala, Ramudu; Parsa, Kishore V. L.; Pal, Manojit
• Is Part Of: RSC advances. Volume 5:Issue 86(2015)
• Page Start: 70604
• Page End: 70608
• Publication Date: 2015-09-18
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c5ra14671b
• Languages: English
• ISSNs: 2046-2069

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj2gzwgs58" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />A two-step strategy involving quinoxaline directed the <italic>ortho</italic> C–H alkenylation/intramolecular <italic>ortho</italic> C–H cycloamination afforded new PDE4 inhibitors.</p> </abstract>