Up-regulation of MSH2, XRCC1 and ATM genes in patients with type 2 diabetes and coronary artery disease. Issue 3 (September 2015)

• Record Type: Journal Article
• Authors: Ahmadi, Amirhossein; Behmanesh, Mehrdad; Boroumand, Mohammad Ali; Tavallaei, Mahmoud
• Is Part Of: Diabetes research and clinical practice. Volume 109:Issue 3(2015)
• Page Start: 500
• Page End: 506
• Publication Date: 2015-09
• Subjects: Diabetes -- Periodicals; Diabetes Mellitus -- Periodicals; 616.462
• DOI: 10.1016/j.diabres.2015.05.049
• Languages: English
• ISSNs: 0168-8227

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Up-regulation of MSH2, XRCC1 and ATM genes was observed in T2DM patients with CAD.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">ATM expression was correlated with CAD severity.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Single nucleotide polymorphisms in their promoters did not affect mRNA expression.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">DNA repair genes expression may serve as useful biomarkers.</p> </list-item> </list> </p> </sec> </abstract>