Impact of diabetes on fibrinogen levels and its relationship with platelet reactivity and coronary artery disease: A single-centre study. Issue 3 (September 2015)

• Record Type: Journal Article
• Authors: Di Giovine, Gabriella; Verdoia, Monica; Barbieri, Lucia; Schaffer, Alon; Aimaretti, Gianluca; Bellomo, Giorgio; Marino, Paolo; Suryapranata, Harry; Sinigaglia, Fabiola; De Luca, Giuseppe; Novara Atherosclerosis Study (NAS) group
• Is Part Of: Diabetes research and clinical practice. Volume 109:Issue 3(2015)
• Page Start: 541
• Page End: 550
• Publication Date: 2015-09
• Subjects: Diabetes -- Periodicals; Diabetes Mellitus -- Periodicals; 616.462
• DOI: 10.1016/j.diabres.2015.05.038
• Languages: English
• ISSNs: 0168-8227

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Contrasting data have been reported on the relationship between fibrinogen and coronary disease.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Enhanced pro-thrombotic status is observed in diabetics, conditioning cardiovascular risk.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">We evaluated the impact of diabetes on fibrinogen levels and CAD in 3280 patients.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Neither diabetes nor glucose homeostasis parameters resulted as independent predictors of hyperfibrinogenemia.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">Among diabetics, fibrinogen elevation did not affect platelet reactivity nor the prevalence of CAD.</p> </list-item> </list> </p> </sec> </abstract>