A member of the Tlr family is involved in dsRNA innate immune response in Paracentrotus lividus sea urchin. Issue 2 (August 2015)

• Record Type: Journal Article
• Authors: Russo, Roberta; Chiaramonte, Marco; Matranga, Valeria; Arizza, Vincenzo
• Is Part Of: Developmental and comparative immunology. Volume 51:Issue 2(2015)
• Page Start: 271
• Page End: 277
• Publication Date: 2015-08
• Subjects: Immunology -- Periodicals; Developmental immunology -- Periodicals; 616.079
• DOI: 10.1016/j.dci.2015.04.007
• Languages: English
• ISSNs: 0145-305X

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010">The expression of a newly isolated <italic>Pl-Tlr</italic> cDNA is up-regulated after polyI:C challenge (viral infection).</p> </list-item> <list-item id="u9010"> <label></label> <p id="p9010"> <italic>Pl-Tlr</italic> is down-regulated in LPS injury (bacterial infection) in <italic>P. lividus</italic> sea urchin immune cells.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">Phylogenetics of Pl-Tlr and Tlr proteins from vertebrates and invertebrates shows the conservative evolutionary process of these proteins.</p> </list-item> </list> </p> </sec> </abstract>