Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system. (September 2015)

• Record Type: Journal Article
• Authors: Yang, Peiran; Maguire, Janet J.; Davenport, Anthony P.
• Is Part Of: Trends in pharmacological sciences. Volume 36:Number 9(2015)
• Page Start: 560
• Page End: 567
• Publication Date: 2015-09
• Subjects: Pharmacology -- Periodicals; Pharmacology -- trends -- Periodicals; Pharmacologie -- Périodiques; Pharmacology; Electronic journals; Periodicals; 615.1
• DOI: 10.1016/j.tips.2015.06.002
• Languages: English
• ISSNs: 0165-6147

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">A biased apelin receptor agonist shows proof-of-concept for utility in the clinic.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Elabela/Toddler is a new apelin receptor ligand in the human cardiovascular system.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Enhancing apelin signalling is beneficial in pulmonary arterial hypertension.</p> </list-item> </list> </p> </sec> </abstract>