Combined atom‐transfer radical polymerization and ring‐opening polymerization to design polymer–polypeptide copolymer conjugates toward self‐aggregated hybrid micro/nanospheres for dye encapsulation. Issue 20 (17th June 2015)

• Record Type: Journal Article
• Authors: Saha, Anupam; Paira, Tapas K.; Biswas, Mrinmoy; Jana, Somdeb; Banerjee, Sanjib; Mandal, Tarun K.
• Is Part Of: Journal of polymer science. Volume 53:Issue 20(2015:Oct.)
• Page Start: 2313
• Page End: 2319
• Publication Date: 2015-06-17
• Subjects: 547
• DOI: 10.1002/pola.27713
• Languages: English
• ISSNs: 0887-624X

Abstract

<abstract abstract-type="graphical"> <title> <x xml:space="preserve">Abstract</x> </title> <p>A designed orthogonal dual initiator is employed to construct poly(methyl methacrylate)‐<italic>block‐</italic>polytyrosine copolymer conjugates via the combination of atom‐transfer radical polymerization of methyl methacrylate, "click" chemistry and ring‐opening polymerization of tyrosine–α‐amino acid <italic>N</italic>‐carboxyanhydride monomer. The polymer–polypeptide conjugate undergoes self‐aggregation in dimethylformamide to produce hybrid micro/nanospheres owing to the formation of composite micelle as evidenced from field emission scanning electron microscopy and dynamic light scattering study. A simple solution‐based approach is described to encapsulate an organic dye (Rhodamine‐6G) into the aggregated hybrid micro/nanospheres. <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgj2hdwfgjz" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></p> </abstract>