Metabolic syndrome in antipsychotic naïve patients with schizophrenia: pooled analysis of data from three Indian studies. Issue 5 (20th January 2014)

• Record Type: Journal Article
• Authors: Grover, Sandeep; Nebhinani, Naresh; Padmavati, Ramachandran; Chadda, Rakesh K; Tirupati, Srinivasan; Pallava, Abhishek
• Is Part Of: Early intervention in psychiatry. Volume 9:Issue 5(2015:Oct.)
• Page Start: 357
• Page End: 362
• Publication Date: 2014-01-20
• Subjects: Mental health -- Periodicals; Psychiatry -- Periodicals; Psychiatry -- Research -- Periodicals; Mental illness -- Prevention -- Research -- Periodicals; Mental illness -- Treatment -- Research -- Periodicals; 616.89
• DOI: 10.1111/eip.12117
• Languages: English
• ISSNs: 1751-7885

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="eip12117-sec-0001" sec-type="section"> <title>Aim</title> <p>This study aimed to assess the prevalence of metabolic syndrome (MS) and subthreshold MS in antipsychotic naïve patients with schizophrenia by pooling the data from three different centres in India.</p> </sec> <sec id="eip12117-sec-0002" sec-type="section"> <title>Methods</title> <p>One hundred thirty‐seven antipsychotic naïve patients with schizophrenia were evaluated for MS using common criteria for clinical diagnosis.</p> </sec> <sec id="eip12117-sec-0003" sec-type="section"> <title>Results</title> <p>Twenty‐six patients (19%) met consensus criteria. Additionally, 56 patients (40.9%) fulfilled one criterion and 32 patients (23.3%) fulfilled two criteria of MS out of five criteria.</p> </sec> <sec id="eip12117-sec-0004" sec-type="section"> <title>Conclusion</title> <p>One‐fifth of antipsychotic naïve patients with schizophrenia had MS and another two‐third had at least one metabolic abnormality. Awareness of such a high risk is vitally important for rational selection of antipsychotic medications as well as effective implementation of preventive measures.</p> </sec> </abstract>