Rotavirus and adenovirus gastroenteritis: time series analysis. Issue 4 (28th April 2015)

• Record Type: Journal Article
• Authors: Celik, Cem; Gozel, Mustafa Gokhan; Turkay, Hakan; Bakici, Mustafa Zahir; Güven, Ahmet Sami; Elaldi, Nazif
• Is Part Of: Pediatrics international. Volume 57:Issue 4(2015)
• Page Start: 590
• Page End: 596
• Publication Date: 2015-04-28
• Subjects: Pediatrics -- Periodicals; 618.92
• DOI: 10.1111/ped.12592
• Languages: English
• ISSNs: 1328-8067

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="ped12592-sec-0001" sec-type="section"> <title>Background</title> <p>This study investigated the effects of changes in weather conditions (monthly average temperature, monthly minimum temperature, monthly average humidity) on rotavirus and adenovirus gastroenteritis frequency and whether there was a seasonal correlation.</p> </sec> <sec id="ped12592-sec-0002" sec-type="section"> <title>Methods</title> <p>Between 2006 and 2012, 4702 fecal samples were taken from patients ≤5 years of age with acute gastroenteritis; these samples were analyzed in terms of rotavirus group A and adenovirus serotype 40–41 antigens using time‐series and negative binomial regression analysis.</p> </sec> <sec id="ped12592-sec-0003" sec-type="section"> <title>Results</title> <p>Rotavirus antigens were found in 797 samples (17.0%), adenovirus antigens in 113 samples (2.4%), and rotavirus and adenovirus antigens together in 16 samples (0.3%). There was a seasonal change in rotavirus gastroenteritis (<italic>P</italic> < 0.001), and a 1°C decrease in average temperature increased the ratio of rotavirus cases in those with diarrhea by 0.523%. In addition, compared with data from other years, the number of patients was lower in the first month of 2008 and in the second month of 2012, when the temperature was below −20°C (monthly minimum temperature). There was no statistically significant relationship between adenovirus infection and change in weather conditions.</p> </sec> <sec id="ped12592-sec-0004" sec-type="section"> <title>Conclusion</title> <p>Various factors such as change in weather conditions, as well as the population's sensitivity and associated changes in activity, play a role in the spread of rotavirus infection.</p> </sec> </abstract>