Relationship between electrocardiographic signs and shunt volume in atrial septal defect. Issue 4 (25th March 2015)

• Record Type: Journal Article
• Authors: Somura, Junpei; Nakagawa, Masao; Ukiami, Masami; Sagawa, Hironori; Furukawa, Ouki; Hoshino, Shinsuke; Fujino, Hidetoshi; Takeuchi, Yoshihiro
• Is Part Of: Pediatrics international. Volume 57:Issue 4(2015)
• Page Start: 535
• Page End: 540
• Publication Date: 2015-03-25
• Subjects: Pediatrics -- Periodicals; 618.92
• DOI: 10.1111/ped.12569
• Languages: English
• ISSNs: 1328-8067

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="ped12569-sec-0001" sec-type="section"> <title>Background</title> <p>The aim of this study was to determine whether electrocardiographic signs correlate with hemodynamics and the magnitude of the intracardiac shunt in children with ostium secundum atrial septal defects (ASD).</p> </sec> <sec id="ped12569-sec-0002" sec-type="section"> <title>Methods</title> <p>A total of 100 ASD patients (median age, 6 years 4 months; 54 girls) underwent cardiac catheterization between August 1980 and April 2010. We retrospectively investigated the relationship between electrocardiographic signs and the pulmonary/systemic blood flow ratio (Qp/Qs) in these patients. We also compared 63 postoperative electrocardiograms with those recorded before surgery.</p> </sec> <sec id="ped12569-sec-0003" sec-type="section"> <title>Results</title> <p>The mean Qp/Qs ratio of the 100 patients was 2.46 ± 0.81 (range, 1.1–5.0). The Qp/Qs ratio in patients with and without right bundle branch block (RBBB) was 2.57 ± 0.82 (<italic>n</italic> = 73) and 2.15 ± 0.72 (<italic>n</italic> = 27), respectively (<italic>P</italic> = 0.016). The Qp/Qs ratio in patients with and without isolated negative T‐wave was 2.85 ± 0.87 (<italic>n</italic> = 38) and 2.22 ± 0.68 (<italic>n</italic> = 62), respectively (<italic>P</italic> = 0.0003). None of the patients with low Qp/Qs ratio (Qp/Qs ratio ≤ 1.5) had both RBBB and isolated negative T‐wave. The prevalence of these two signs decreased from 73.0% (<italic>n</italic> = 46) and 36.5% (<italic>n</italic> = 23) to 15.9% (<italic>n</italic> = 10) and 15.9% (<italic>n</italic> = 10) after surgical repair, respectively.</p> </sec> <sec id="ped12569-sec-0004" sec-type="section"> <title>Conclusions</title> <p>RBBB and isolated negative T‐wave in the precordial leads are well correlated with high Qp/Qs ratio in ASD patients.</p> </sec> </abstract>