International survey on definitions and current practices in prevention, diagnosis, management and reporting of transfusion‐transmitted bacterial infections. (3rd June 2015)

• Record Type: Journal Article
• Authors: Chew, E.; Benjamin, R. J.; McDonald, C. P.; Wiersum‐Osselton, J. C.; Wood, E. M.; the International Society of Blood Transfusion Working Parties on Transfusion‐Transmitted Infectious Diseases (Bacterial subgroup) and Haemovigilance
• Is Part Of: ISBT science series. Volume 10:Number 1(2015)
• Page Start: 31
• Page End: 40
• Publication Date: 2015-06-03
• Subjects: Blood -- Periodicals; Blood -- Transfusion -- Periodicals; Immunohematology -- Periodicals; Immunopathology -- Periodicals; 615.39
• DOI: 10.1111/voxs.12176
• Languages: English
• ISSNs: 1751-2816

Abstract

<abstract abstract-type="main" id="voxs12176-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="voxs12176-sec-0001" sec-type="section"> <title>Background and objectives</title> <p>Transfusion‐transmitted bacterial infections (TTBI) remain a threat to safe blood transfusion. Currently, there is no consensus on the definition, presentation, management and prevention of TTBI. A common set of criteria would facilitate haemovigilance and benchmarking. An international survey to assess current practices in TTBI was performed as part of efforts in developing an accepted TTBI definition.</p> </sec> <sec id="voxs12176-sec-0002" sec-type="section"> <title>Material and Methods</title> <p>After a pilot study, the questionnaire was sent via a web‐based survey (<ext-link ext-link-type="uri" xlink:href="http://www.surveymonkey.com" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">www.surveymonkey.com</ext-link>) to members of the International Society of Blood Transfusion (ISBT) Working Parties on Transfusion‐Transmitted Infectious Diseases (bacterial subgroup) and Haemovigilance as well as members of the transfusion community with an interest in transfusion safety.</p> </sec> <sec id="voxs12176-sec-0003" sec-type="section"> <title>Results</title> <p>Results from 58 respondents in 39 countries were available. Twenty‐seven countries had a haemovigilance programme. A TTBI definition was available from 27 respondents (17 countries). The reported clinical presentation and management of TTBI, and procedures to prevent bacterial contamination and screening of blood products varied amongst the respondents. The most frequently cited signs of a TTBI were fever, tachycardia, rigours and hypotension. Common methods to prevent bacterial contamination of blood products included donor health questionnaire, skin disinfection prior to blood collection and use of a diversion pouch. Routine bacterial screening of blood products was performed in 19 countries.</p> </sec> <sec id="voxs12176-sec-0004" sec-type="section"> <title>Conclusion</title> <p>This survey highlighted the different practices in TTBI globally and provides a baseline for ongoing endeavours to harmonize TTBI definitions and management.</p> </sec> </abstract>